Dr Ronald Chin checks out Malignant Tumours of the Nasal Cavity & Paranasal Sinuses1
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Dr Ronald Chin checks out Malignant Tumours of the Nasal Cavity & Paranasal Sinuses

Malignant Tumors of the Nasal Cavity and Paranasal Sinuses

Cancers affecting the nasal cavity and paranasal sinuses are uncommon but can be aggressive. They are part of a broader category of head and neck malignancies, which can also impact the oral cavity, pharynx, larynx, salivary glands, and thyroid.

Diagnosis & Evaluation
A thorough clinical history and examination are essential in evaluating these cancers. Diagnostic steps typically include:

  • Nasal endoscopy with biopsy
  • Imaging scans such as CT, MRI, or PET
  • Chest X-ray (CXR) and neck CT for further assessment

Epidemiology

  • Malignant nasal and sinus tumors are rare
  • Most commonly affect the nasal cavity, followed by the maxillary sinus
  • More frequently diagnosed in men than in women
  • The average age of onset is in the sixth decade of life

Common Types of Tumors

  • Squamous cell carcinoma (SCC) – the most prevalent type
  • Adenocarcinoma
  • Neuroendocrine tumors
  • Mucosal melanomas

Risk Factors

  • Tobacco use
  • Occupational exposure to substances such as wood dust and adhesives

Symptoms & Clinical Presentation

  • Often detected late, as early symptoms can be subtle
  • Initial symptoms: Nasal blockage, nosebleeds (epistaxis)
  • Advanced symptoms:
  • Facial swelling
  • Vision disturbances (double vision, bulging eyes)
  • Cranial nerve involvement

Investigations
To confirm a diagnosis, the following tests are used:

  • Endoscopy (to visualize abnormalities)
  • Biopsy (to determine malignancy)
  • Imaging (CT/MRI/PET for tumor assessment and staging)

Treatment Options
The main treatment approach includes:

  • Surgical removal of the tumor
  • Postoperative radiation therapy to reduce recurrence risk

Key Consideration
A malignant tumor should be suspected in patients with persistent unilateral sinusitis that does not improve with standard treatment. Early detection is critical for better treatment outcomes.

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