Dr Ronald Chin checks out Malignant Tumours of the Nasal Cavity & Paranasal Sinuses
Malignant Tumors of the Nasal Cavity and Paranasal Sinuses
Cancers affecting the nasal cavity and paranasal sinuses are uncommon but can be aggressive. They are part of a broader category of head and neck malignancies, which can also impact the oral cavity, pharynx, larynx, salivary glands, and thyroid.
Diagnosis & Evaluation
A thorough clinical history and examination are essential in evaluating these cancers. Diagnostic steps typically include:
- Nasal endoscopy with biopsy
- Imaging scans such as CT, MRI, or PET
- Chest X-ray (CXR) and neck CT for further assessment
Epidemiology
- Malignant nasal and sinus tumors are rare
- Most commonly affect the nasal cavity, followed by the maxillary sinus
- More frequently diagnosed in men than in women
- The average age of onset is in the sixth decade of life
Common Types of Tumors
- Squamous cell carcinoma (SCC) – the most prevalent type
- Adenocarcinoma
- Neuroendocrine tumors
- Mucosal melanomas
Risk Factors
- Tobacco use
- Occupational exposure to substances such as wood dust and adhesives
Symptoms & Clinical Presentation
- Often detected late, as early symptoms can be subtle
- Initial symptoms: Nasal blockage, nosebleeds (epistaxis)
- Advanced symptoms:
- Facial swelling
- Vision disturbances (double vision, bulging eyes)
- Cranial nerve involvement
Investigations
To confirm a diagnosis, the following tests are used:
- Endoscopy (to visualize abnormalities)
- Biopsy (to determine malignancy)
- Imaging (CT/MRI/PET for tumor assessment and staging)
Treatment Options
The main treatment approach includes:
- Surgical removal of the tumor
- Postoperative radiation therapy to reduce recurrence risk
Key Consideration
A malignant tumor should be suspected in patients with persistent unilateral sinusitis that does not improve with standard treatment. Early detection is critical for better treatment outcomes.